教育背景

07/2019–至今，博士后，暨南大学第一临床医学院

07/2016–07/2019，博士（再生医学），暨南大学

09/2013–06/2016，硕士（药剂学），暨南大学

09/2008–06/2012，本科（药学），河南中医药大学

发表论文

1. Yuanyuan You, Zhennan Zhao, Lizhen He, Zhibo Sun, Dong Zhang, Changzheng Shi, Qingqing Cheng, Yiyong Liu, Liangping Luo, Tianfeng Chen*. Long-term Oxygen Storage Nanosystem for Near-Infrared Light-Triggered Oxygen Supplies to Antagonize Hypoxia-induced Therapeutic Resistance in Nasopharyngeal Carcinoma. Advanced Functional Materials. 2020, 2002369.

2. Yuanyuan You#, Ni Wang#, Lizhen He, Changzheng Shi, Dong Zhang, Yiyong Liu, Liangping Luo, Tianfeng Chen*. Designing Dual-functionalized Carbon Nanotubes with High Blood-brain-Barrier Permeability for Precise Orthotopic Glioma Therapy, Dalton Transactions, 2019, 48, 1569-1573.

3. Yuanyuan You, Lizhen He, Bin Ma, Tianfeng Chen*. High-drug loading mesoporous silica nanorods with reduced toxicity for precise cancer therapy against nasopharyngeal carcinoma. Advanced Functional Materials. 2017, 27, 1703313.

4.Yuanyuan You, Liye Yang, Lizhen He, Tianfeng Chen*. Tailored mesoporous silica nanosystem with enhanced permeability of blood-brain barrier to antagonize glioblastoma. J. Mater. Chem. B, 2016,4, 5980-5990. (Cover)

5.Yuanyuan You#, Liye Yang#, Lizhen He, Tianfeng Chen*, Tailored mesoporous silica nanosystem with enhanced permeability of blood‐brain barrier to antagonize glioblastoma, J. Mater. Chem. B 2016, 4, 5980-5990.

6.Yuanyuan You, Hao Hu, Lizhen He, and Tianfeng Chen*. Differential Effects of Polymer-Surface Decoration on Drug Delivery, Cellular Retention, and Action Mechanisms of Functionalized Mesoporous Silica Nanoparticles. Chemistry-An Asian Journal. 2015, 10, 2744–2754. (Cover)

7.Yuanwei Liang, Delong Zeng, Yuanyuan You, Bin Ma, Xiaoling Li, Tianfeng Chen*. Designing Dihydrofolate Reductase Inhibitors as X-ray Radiosensitizers to Reverse Radioresistance of Cervical Cancer. ACS Medicinal Chemistry Letters, 2020, 11, 1421-1428.

8. Xiaoxuan Mai#, Yanzhou Chang#, Yuanyuan You, Lizhen He*, Tianfeng Chen*. Designing Intelligent Nano-bomb with On-demand Site-specific Drug Burst Release to Synergize with High-Intensity Focused Ultrasound Cancer Ablation, Journal of Controlled Release, 2021,  331, 270–281.

9. Yuanwei Liang, Delong Zeng, Yuanyuan You, Bin Ma, Xiaoling Li, and Tianfeng Chen*. Designing Dihydrofolate Reductase Inhibitors as X‑ray Radiosensitizers to Reverse Radioresistance of Cervical Cancer, ACS Med. Chem. Lett., 2020, 11, 7, 1421–1428.

10. Bin Ma, Lizhen He*, Yuanyuan You, Jianbin Mo, Tianfeng Chen*. Controlled synthesis and size effects of multifunctional mesoporous silica nanosystem for precise cancer therapy. Drug Delivery, 2018, 25, 293–306.

11. Xiaobin Zhang^#, Chengli Dai^#, Yuanyuan You, Lizhen He*, Tianfeng Chen*. Tea Regimen, a Comprehensive Assessment of Antioxidant and Antitumor Activities of Tea Extract Produced by Tie Guanyin Hybridization. RSC Advances, 2018, 8, 11305 – 11315.

12. Xiaobin Zhang, Zhenhuan Song, Yuanyuan You, Xiaoling Li*, Tianfeng Chen*. Phoenix Dan Cong Tea：An Oolong Tea variety with promising antioxidant and in vitro anticancer activity. Food & Nutrition Research. 2018, 62: 1500.

13. Zhennan Zhao, Pan Gao, Yuanyuan You and Tianfeng Chen*. Cancer-targeting Functionalization of Selenium-Containing Ruthenium Conjugate with Tumor Microenvironment-Responsive Property to Enhance Theranostic Effects. Chem. Eur. J., 2018, 24, 3289-3298.

14. Yanzhou Chang, Lizhen He, Zhibin Li, Lilan Zeng, Zhenhuan Song, Penghui Li, Leung Chan, Yuanyuan You, Xue-Feng Yu*, Paul K Chu, and Tianfeng Chen*. Designing Core-Shell Gold and Selenium Nanocomposites for Cancer Radiochemotherapy. ACS Nano, 2017, 11(5):4848-4858.

15. Lizhen He, Yanyu Huang,  Yanzhou Chang,  Yuanyuan You,  Hao Hu,  Kam Leong*  and  Tianfeng Chen*. A Highly Selective Dual-therapeutic Nanosystem for Simultaneous Anticancer and Antiangiogenesis, Journal of Materials Chemistry B, 2017, in press.

16. Wei Huang, Yanyu Huang, Yuanyuan You, Tianqi Nie, Tianfeng Chen*. High-yield synthesis of multifunctional tellurium nanorods to achieve simultaneous chemophotothermal combination cancer therapy. Advanced Functional Materials. 2017, 27, 1701388.

17. Zhiqin Deng, Pan Gao, Lianling Yu, Bin Ma, Yuanyuan You, Leung Chan, Chaoming Mei, Tianfeng Chen*. Ruthenium complexes with phenylterpyridine derivatives target cell membrane and trigger death receptors-mediated apoptosis in cancer cells. Biomaterials, 2017, 129, 111-126.

18. Mingxian Liu*, Yanzhou Chang, Jing Yang, Yuanyuan You, Rui He, Tianfeng Chen* and    Changren Zhou. Functionalized halloysite nanotube by chitosan grafting for drug delivery of curcumin to achieve enhanced anticancer efficacy. J. Mater. Chem. B, 2016,4, 2253-2263.

19. Hao Hu, Yuanyuan You, Lizhen He, Tianfeng Chen*. Rational design of NAMI-A-loaded mesoporous silica nanoparticles as antiangiogeneic nanosystem. J. Mater. Chem. B, 2015, 3, 6338 - 6346.

20. Lizhen He, Tianfeng Chen*, Yuanyuan You, Hao Hu, Wenjie Zheng, Wai-Lun Kwong, Taotao Zou and Chi-Ming Che*. A Cancer-Targeted Nanosystem for Delivery of Anti-Cancer Gold(III) Complexes: Enhanced Selectivity and Apoptosis-Inducing Efficacy of Gold(III) Porphyrin. Angew Chem Int Edit, 2014, 53(46), 12532-12536.

获奖情况

1. 2015年硕士国家奖学金

2. 2016年“傅家谟”奖学金

3. 2016年暨南大学论文创新奖

4. 2017年博士国家奖学金

5. 2018年暨南大学学术创新优秀成果奖

6. 第六届国际硒会墙报奖

7. 第四届实验室学术比赛墙报奖一等奖

8. 广东省第三届材料创新大赛三等奖