2016-2014年文章汇总

1.Yanyu Huang, Wei Huang, Leung Chan, Binwei Zhou, Tianfeng Chen*. A multifunctional DNA origami as carrier of metal complexes to achieve enhanced tumoral delivery and nullified systemic toxicity. Biomaterials, 2016, 103, 183–196.

2.Sin Ki Fung, Taotao Zou, Bei Cao, Tianfeng Chen, Wai-Pong To, Chen Yang, Chun-Nam Lok& Chi-Ming Che*. Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and a basic DNA. Nature Communications, 2016, 7, 10655.

3.Ting Liu, Lanhai Lai, Zhenhuan Song, Tianfeng Chen*. A Sequentially triggered nanosystem for precise drug delivery and simultaneous inhibition of cancer growth, migration and invasion. Advanced Functional Materials. 2016, 26, 7775–7790. (Inside Cover)

5.Leung Chan, Yanyu Huang, Tianfeng Chen*. Cancer-targeted Tri-block Copolymer Nanoparticles as Payload of Metal Complexes to Achieve Enhanced Cancer Theranosis. J. Mater. Chem. B, 2016, 4, 4517.

6.Yuanwei Liang, Yangliang Zhou, Shulin Deng, Tianfeng Chen*. Microwave-assisted syntheses of benzimidazole-containing selenadiazole derivatives that induce cell cycle arrest/apoptosis in human breast cancer cells via activation of ROS/AKT pathway. ChemMedChem, 2016 11(20):2339-2346.

7.Yahui Yang, Shulin Deng, Qinsong Zeng*, Weilie Hu, Tianfeng Chen*.Highly stable selenadiazole derivatives induce bladder cancer cell apoptosis and inhibit cell migration and invasion through activation of ROS-mediated signaling pathways. Dalton Transactions, 2016, 45, 18465-18475. (Inside front cover)

8.Johnson Lui-Lui Tsai, Taotao Zou, Jia Liu, Tianfeng Chen, Anna On-Yee Chan, Chen Yang, Chun-Nam Lok and Chi-Ming Che*. Luminescent platinum(II) complexes with self-assembly and anti-cancer properties: hydrogel, pH dependent emission color and sustained-release properties under physiological conditions.Chem. Sci., 2015,6, 4623-4635.

9.Jingjing Chen, Zuandi Luo, Zhennan Zhao, Lina Xie, Wenjie Zheng, Tianfeng Chen*. Data on the characterization and anticancer action of iron(II) polypyridyl complexes.Data in Brief, 2016, 8: 670–686.

10.Meng Li#, Lanhai Lai#, Zhennan Zhao, Tianfeng Chen*. Aquation Is a Crucial Activation Step for Anticancer Action of Ruthenium(II) Polypyridyl Complexes to Trigger Cancer Cell Apoptosis.Chemistry-An Asian Journal, 2016, 11, 310-320.

11.Hu, YF; Ma, YT; Wu, S ; Chen, TF; He, Y; Sun, JX; Jiao, R; Jiang, XW ; Huang, YD; Deng, LH; Bai, WB, Protective Effect of Cyanidin-3-O-Glucoside against Ultraviolet B Radiation-Induced Cell Damage in Human HaCaT Keratinocytes,FRONTIERS IN PHARMACOLOGY, 2016, 7, 301.

12.Binwei Zhou, Yanyu Huang, Fang Yang,* Wenjie Zheng, Tianfeng Chen*. Dual-functional nanographene oxide as cancer-targeted drug delivery system to selectively induce cancer cell apoptosis. Chemistry-An Asian Journal, 2016, 11, 1008–1019.

13.Bo Yu, Ting Liu, Yanxin Du, Zuandi Luo, Wenjie Zheng and Tianfeng Chen*. X-ray-responsive Selenium Nanoparticles for Enhanced Cancer Chemo-radiotherapy. Colloids and Surfaces B: Biointerfaces. 2016, 139, 180–189.

14.Xiaoyan Fu, Yahui Yang, Xiaoling Li, Haoqiang Lai, Yanyu Huang, Lizhen He, Wenjie Zheng, Tianfeng Chen *. RGD Peptide-conjugated Selenium Nanoparticles: Antiangiogenesis by Suppressing VEGF-VEGFR2-ERK/AKT Pathway. Nanomedicine: Nanotechnology, Biology, and Medicine, 2016, 12, 1627–1639.

15.Tianqi Nie#, Hualian Wu#, Ka-Hing Wong*, Tianfeng Chen*. Facial synthesis of highly uniform selenium nanoparticles using glucose as reductant and surface decorator to induce cancer cell apoptosis. J. Mater. Chem. B, 2016,4, 2351-2358.

16.Mo, Jianbin; He, Lizhen; Ma, Bin; Chen, Tianfeng*. Tailoring Particle Size of Mesoporous Silica Nanosystem to Antagonize Glioblastoma and Overcome Blood-brain Barrier. ACS Applied Materials & Interfaces. 2016, 8(11):6811-6825.

17.Mingxian Liu*, Yanzhou Chang, Jing Yang, Yuanyuan You, Rui He, Tianfeng Chen* andChangren Zhou. Functionalized halloysite nanotube by chitosan grafting for drug delivery of curcumin to achieve enhanced anticancer efficacy. J. Mater. Chem. B, 2016,4, 2253-2263.

18.Wei Huang, Hualian Wu, Xiaoling Li*, Tianfeng Chen*. Facile one-pot synthesis of tellurium nanorods as antioxidant and anticancer agents. Chemistry-An Asian Journal, 2016, 11(16):2301-11.

19.Yuanyuan You, Liye Yang, Lizhen He, Tianfeng Chen*. Tailored mesoporous silica nanosystem with enhanced permeability of blood-brain barrier to antagonize glioblastoma. J. Mater. Chem. B, 2016,4, 5980-5990. (Cover)

20.Zhou Liu, Leung Chan, Li Yan Chen, Yan Bai*, Tianfeng Chen*.Facile Fabrication of Near-Infrared Responsive and Chitosan-functionalized Cu2Se Nanoparticles for Cancer Photothermal Therapy. Chemistry-An Asian Journal, 2016, 11 (21) 3032-3039. (Cover)

21.Li, YH ; Guo, M; Lin, ZF; Zhao, MQ; Xiao, MS; Wang, CB ; Xu, TT; Chen, TF* ; Zhu, B, Polyethylenimine-functionalized silver nanoparticle-based co-delivery of paclitaxel to induce HepG2 cell apoptosis, INTERNATIONAL JOURNAL OF NANOMEDICINE, 2016,11, 6693-6702.

22.Lilan Zeng, Jingjing Chen, Shengbin Ji, Leung Chan, Wenjie Zheng, Tianfeng Chen*. Construction of cancer-targeted nanosystem as payload of iron complexes to reverse cancer multidrug resistance. J. Mater. Chem. B, 2015,3, 4345-4354. (Back Cover)

23.Hao Hu, Yuanyuan You, Lizhen He, Tianfeng Chen*. Rational design of NAMI-A-loaded mesoporous silica nanoparticles as antiangiogeneic nanosystem. J. Mater. Chem. B, 2015, 3, 6338 – 6346.

24.Ni Wang, Yanxian Feng, Lilan Zeng, Zhennan Zhao, Tianfeng Chen*.Functionalized Multi-Walled Carbon Nanotubes as Carriers of Ruthenium Complexes to Antagonize Cancer Multidrug Resistance and Radioresistance. ACS Applied Materials & Interfaces. 2015, 7, 14933-45.

25.Yuanyuan You, Hao Hu, Lizhen He, and Tianfeng Chen*. Differential Effects of Polymer-Surface Decoration on Drug Delivery, Cellular Retention, and Action Mechanisms of Functionalized Mesoporous Silica Nanoparticles. Chemistry-An Asian Journal. 2015, 10, 2744–2754. (Cover)

26.Haoqiang Lai, Zhennan Zhao, Linlin Li, Wenjie Zheng, Tianfeng Chen*. Antiangiogenic ruthenium(II) benzimidazole complexes, structure-based activation of distinct signaling pathways. Metallomics, 2015,7, 439-447 (Front Cover)

27.Lijuan Ma, Yuanting Fu, Lianling Yu, Xiaoling Li*, Wenjie Zheng, Tianfeng Chen*.Ruthenium complexes as inhibitors of human islet amyloid polypeptide aggregation, an effect that prevents beta cell apoptosis.RSC Advances. 2015, 5, 17405-17412.

28.Wenqiang Cao, Wenjie Zheng & Tianfeng Chen*. Ruthenium Polypyridyl Complex Inhibits Growth and Metastasis of Breast Cancer Cells by Suppressing FAK signaling with Enhancement of TRAIL-induced Apoptosis.Scientific Reports. 2015, 5, 9157

29.Zhiqin Deng, Lianling Yu, Wenqiang Cao, Wenjie Zheng and Tianfeng Chen*. Rational design of ruthenium complexes containing 2, 6-bis (benzimidazolyl) pyridine derivatives with radiosensitization activity by enhancing p53 activation.ChemMedChem, 2015, 10,, 991-998. (Inside Cover)

30.Ting Liu, Lilan Zeng, Wenting Jiang, Yuanting Fu, Wenjie Zheng, Tianfeng Chen*. Rational Design of cancer-targeted selenium nanoparticles to antagonize multidrug resistance in cancer cells. Nanomedicine: Nanotechnology, Biology, and Medicine. 2015, 11, 947–958.

31.Bo Yu, Hong Li, Jinhui Zhang, Wenjie Zheng and Tianfeng Chen*. Rational Design and Fabrication of Cancer-targeted Chitosan Nanocarrier to Enhance Selective Cellular Uptake and Anticancer Efficacy of Selenocystine. J. Mater. Chem. B, 2015,3, 2497-2504.

32.Yifan Wang, Wenying Li, Yahui Yang, Qinsong Zeng, Ka-Hing Wong, Xiaoling Li* and Tianfeng Chen*. An integrin-targeting nanosystem as a carrier of the selenadiazole derivative to induce ROS-mediated apoptosis in bladder cancer cells, from rational design to action mechanisms. J. Mater. Chem. B, 2015, 3, 9374-9382.

33.Lizhen He, Shengbin Ji, Haoqiang Lai and Tianfeng Chen*. Selenadiazole Derivatives as Theranostic Agents for Simultaneous Cancer Chemo-/Radiotherapy by Targeting Thioredoxin Reductase. J. Mater. Chem. B, 2015, 3, 8383 – 8393.

34.Yuedan Liu, Yi Luo, Xiaoling Li*, Wenjie Zheng, Tianfeng Chen*. Rational design of selenadiazole derivatives to antagonize hyperglycemia-induced drug resistance in cancer cells. Chemistry-An Asian Journal. 2015. 10, 3, 642–652. (Back Cover)

35.Meiyun Zhou, Shengbin Ji, Zhaojun Wu, Yiqun Li, Wenjie Zheng, Hua Zhou, Tianfeng Chen*. Synthesis of selenazolopyridine derivatives with capability to induce apoptosis in human breast carcinoma MCF-7 cells through scavenge of intracellular ROS. European Journal of Medicinal Chemistry. 2015; 96:92-97.

36.Liye Yang#, Wenying Li#, Yanyu Huang, Yangliang Zhou, Tianfeng Chen*. Rational design of cancer-targeted benzoselenadiazole by RGD peptide functionalization for cancer theranostics. Macromolecular Rapid Communications, 2015, 36(17):1559-65. (Cover)

37.Jingjing Chen#, Zuandi Luo#, Zhennan Zhao, Lina Xie, Wenjie Zheng, Tianfeng Chen*. Cellular Localization of Iron(II) Polypyridyl Complexes Determines Their Anticancer Action Mechanisms. Biomaterials, 2015, 71, 168-177.

38.Zhiqin Deng#, Lianling Yu#, Wenqiang Cao, Wenjie Zheng,* and Tianfeng Chen*. Selenium-containing ruthenium complex as cancer radiosensitizer, rational design and important role of ROS-mediated signaling. Chemical Communications, 2015, 51, 2637 – 2640.

39.Zhong, Y ; Chen, TF; Zheng, WJ ; Yang, YF, Selenium enhances antioxidant activity and photosynthesis in Ulva fasciata,JOURNAL OF APPLIED PHYCOLOGY, 2015, 27(1), 555-562.

40.Jianping Chen, Lin Li, Jianyu Su* and Tianfeng Chen*.Natural borneol enhances bisdemethoxycurcumin-induced cell cycle arrest in the G2/M phase through up-regulation of intracellular ROS in HepG2 cells.Food Funct., 2015,6, 740-748.

41.Jianping Chen, Lin Li, Jianyu Su*, Bing Li, Tianfeng Chen*, Fengqing Ling, Xia Zhang. Enhancing effect of natural borneol on the cellular uptake of demethoxycurcumin and their combined induction of G2/M arrest in HepG2 cells via ROS generation.Journal of Functional Foods. 2015, 17:103-114.

42.Chen, Jianping; Lin, Li; Su, Jianyu*; Li, Bing; Zhang, Xia; Chen, Tianfeng*. Proteomic analysis of G2/M arrest triggered by natural borneol/curcumin in HepG2 cells, the importance of ROS-p53 pathway. Journal of Agricultural and Food Chemistry, 2015, 63, 6440-9.

43.Wenting Jiang, Yuanting Fu, Fang Yang,*, Yufeng Yang, Ting Liu, Wenjie Zheng *, Lilan Zeng, Tianfeng Chen*. Gracilaria Lemaneiformis Polysaccharide as Integrin Targeting Surface Decorator of Selenium Nanoparticles to Achieve Enhanced Anticancer Efficacy. ACS Applied Materials & Interfaces, 2014, 6 (16), 13738–13748.

44.Yanxian Feng, Jianyu Su, Zhennan Zhao, Wenjie Zheng*, Hualian Wu, Yibo Zhang and Tianfeng Chen*. Differential effects of amino acid surface decoration on the anticancer efficacy of selenium nanoparticles. Dalton Transactions. 2014, 43 (4), 1854 - 1861.

45.Bo Yu, Xiaoling Li, Wenjie Zheng,* Yanxian Feng, Yum-Shing Wong and Tianfeng Chen*.pH-Responsive Cancer-targeted Selenium Nanoparticles: A Transformable Drug Carrier with Enhanced Theranostic Effects, J. Mater. Chem. B, 2014, 2 (33), 5409 – 5418

46.Zhang, Y; Wang, JH; Zheng, WJ; Chen, TF ; Tong, QX; Li, D, An ESIPT fluorescent dye based on HBI with high quantum yield and large Stokes shift for selective detection of Cys, JOURNAL OF MATERIALS CHEMISTRY B, 2014, 2( 26), 4159-4166.

47.Lizhen He, Yanyu Huang, Huili Zhu, Guanhua Pang, Wenjie Zheng, Yum-Shing Wong, Tianfeng Chen*. Cancer-targeted Monodisperse Mesoporous Silica Nanoparticles as Carrier of Ruthenium Polypyridyl Complexes to Enhance Theranostic Effects. Advanced Functional Materials. 2014, 24(19), 2754–2763. (封面文章)

48.Lizhen He, Tianfeng Chen*, Yuanyuan You, Hao Hu, Wenjie Zheng, Wai-Lun Kwong, Taotao Zou and Chi-Ming Che*. A Cancer-Targeted Nanosystem for Delivery of Anti-Cancer Gold(III) Complexes: Enhanced Selectivity and Apoptosis-Inducing Efficacy of Gold(III) Porphyrin. Angew Chem Int Edit, 2014, 53(46), 12532-12536.

49.Yanyu Huang, Lizhen He, Wen Liu, Cundong Fan, Wenjie Zheng*, Yum-Shing Wong, Tianfeng Chen*. Selective Cellular Uptake and Induction of Apoptosis of Cancer-targeted Selenium Nanoparticles.Biomaterials, 2013, 34, 7106-7116.

50.Chen, JP; Li, L; Su, JY; Li, B; Chen, TF; Wong, YS, Synergistic Apoptosis-Inducing Effects onA375 Human Melanoma Cells of Natural Borneol and Curcumin,PLOS ONE, 2014, 9(6), e101277

51.Jun-Yi Xue, Guang-Xiong Zhou, Tianfeng Chen*, Si Gao, Mei-Yuk Choi, Yum-Shing Wong*. Desacetyluvaricin Induces S Phase Arrest in SW480 Colorectal Cancer Cells by Regulating Cell Cycle Progression and Induction of Superoxide Generation.Journal of Cellular Biochemistry, 2014, 115, 464-475.

52.Ling Zhao, Jianyu Su,*, Lin Li, Jianping Chen, Songqing Hu, Xia Zhang, Tianfeng Chen*. Mechanistic elucidation of apoptosis and cell cycle arrest induced by 5-hydroxymethylfurfural, the important role of ROS-mediated signaling pathways.Food Research International, 2014, 66, 186-196.

53.Fang Yang, Ka-Hing Wong, Yufeng Yang, Xiaoling Li*, Jie Jiang, Wenjie Zheng*, Hualian Wu, Tianfeng Chen. Purification and in vitro antioxidant activities of tellurium-containing phycobiliproteins from tellurium-enriched Spirulina platensis. Drug Design, Development and Therapy, 2014, 8, 1789-1800.

54.Yanyu Huang, Yi Luo, Wenjie Zheng, and Tianfeng Chen*. Rational design of cancer-targeted BSA protein nanoparticles as radiosensitizer to overcome cancer radioresistance. ACS Applied Materials & Interfaces, 2014, 6(21):19217-28.

55.Cundong Fan, Wenjie Zheng, Xiaoyan Fu, Xiaoling Li, Yum-Shing Wong, Tianfeng Chen*. Enhancement of auranofin-induced lung cancer cell apoptosis by selenocystine, a natural inhibitor of TrxR1 in vitro and in vivo. Cell Death & Disease volume, 2014, 5, e1191.

56.Zhang, YK; Zheng, SY; Ngai, SM; Zheng, WJ ; Li, JY; Chen, TF; Zhong, XY,A Novel Selenadiazole Derivative Induces Apoptosis in Human Glioma Cells by Dephosphorylation of AKT. CHEMICAL & PHARMACEUTICAL BULLETIN, 2014, 62(10 ),994-999

57.Cundong Fan, Wenjie Zheng*, Xiaoyan Fu, Xiaoling Li, Yum-Shing Wong, Tianfeng Chen*. Strategy to enhance the therapeutic effect of doxorubicin in human hepatocellular carcinoma by selenocystine, a synergistic agent that regulates the ROS-mediated signaling. Oncotarget, 2014, 5(9), 2853-2863.

58.Yibo Zhang , Shanyuan Zheng , Jun-Sheng Zheng , Ka-Hing Wong , Zhi Huang , Sai-Ming Ngai , Wenjie Zheng*, Yum-Shing Wong , and Tianfeng Chen*. Synergistic induction of apoptosis by methylseleninic acid and cisplatin, the role of ROS-ERK/AKT-p53 pathway. Mol. Pharmaceutics, 2014, 11 (4), 1282–1293

59.Qiang Xie; Yangliang Zhou; Guoqiang Lan ; Liye Yang; Wenjie Zheng; Yuanwei Liang; Tianfeng Chen*. Sensitization of cancer cells to radiation by selenadiazole derivatives by regulation of ROS-mediated DNA damage and ERK and AKT pathways. Biochemical and Biophysical Research Communications, 2014, 449, 88-93.

60.Yuanwei Liang, Junsheng Zheng, Xiaoling Li*, Wenjie Zheng, Tianfeng Chen*. Selenadiazole derivatives as potent thioredoxin reductase inhibitors that enhance the radiosensitivity of cancer cells. European Journal of Medicinal Chemistry, 2014, 84 335-342.

61.Qiang Xie, Lizhen He, Haoqiang Lai, Wenjie Zheng, Tianfeng Chen*. Selenium substitution endows cystine the radiosensitization activity against cervical cancer cells. RSC Advances, 2014, 4 (64), 34210 - 34216.

62.Wenqiang Cao, Xiaoling Li, Shanyuan Zheng, Wenjie Zheng*, Yum-shing Wang and Tianfeng Chen*. Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk. Oncotarget, 2014, 5, 7431-7445.

63.Qiang Xie, Guoqiang Lan, Yangliang Zhou, Jiamin Huang, Yuanwei Liang, Wenjie Zheng, Xiaoyan Fu, Cundong Fan, Tianfeng Chen*. Strategy to enhance the anticancer efficacy of x-ray radiotherapy in melanoma cells by platinum complexes, the role of ROS-mediated signaling pathways. Cancer Letters, 2014, 354, 58-67.

64.Zhennan Zhao, Zuandi Luo, Qiong Wu, Wenjie Zheng*, Yanxian Feng and Tianfeng Chen*. Mixed-ligand ruthenium polypyridyl complexes as apoptosis inducers in cancer cells, the cellular translocation and the important role of ROS-mediated signaling. Dalton Trans., 2014,43, 17017-17028. (Front Cover)

65.Cundong Fan, Qiong Wu, Tianfeng Chen*, Yibo Zhang, Wen-Jie Zheng*, Qi Wang and Mei Wen-Jie*. Arene ruthenium(II) complexes induce S-phase arrest in MG-63 cells through stabilization of c-myc G-quadruplex DNA.Med. Chem. Commun., 2014, 5 (5), 597 - 602.

66.Yanxin Du, Xiaoyan Fu, Hong Li, Bolai Chen,* Yuhai Guo, Guoyi Su, Hu Zhang, Feipeng Ning, Yongpeng Lin, Wenjie Mei, and Tianfeng Chen*. Mitochondrial fragmentation is an important cellular event induced by ruthenium(II) polypyridyl complexes in osteosarcoma cells.ChemMedChem. 2014, 9, 714-718.

67.Qiang Xie, Shenggui Liu, Xiaoling Li, Qiong Wu, Zuandi Luo, Xiaoyan Fu, Wenqiang Cao, Guoqiang Lan, Dan Li,* Wenjie Zheng, Tianfeng Chen*. Dinuclear Zinc(II) Complexes Containing (Benzimidazo1-2-yl)benzene That Overcome Drug Resistance in Hepatocellular Carcinoma Cells through Induction of Mitochondria Fragmentation.Dalton Transactions. 2014, 43 (19), 6973 - 6976

68.Qiong Wu,# Tianfeng Chen,# (co-first author) Zhao Zhang, Siyan Liao, Xiaohui Wu, Jian Wu, Wenjie Mei,* Yanhua Chen, Weili Wu, Lingli Zeng, and Wenjie Zheng*. Microwave-assisted synthesis of arene ruthenium(II) complexes [(η6-RC6H5)Ru(m-MOPIP)Cl]Cl ( R= -H and -CH3) as groove binder to c-myc G4 DNA.Dalton Transactions. 2014, 43, 9216-9225

69.Zuandi Luo, Lianling Yu, Fang Yang, Zhennan Zhao, Bo Yu, Haoqiang Lai, Ka-Hing Wong, Sai-Ming Ngai, Wen-Jie Zheng* and Tianfeng Chen*, Ruthenium polypyridyl complexes as inducer of ROS-mediated apoptosis in cancer cells by targeting thioredoxin reductase. Metallomics, 2014, 6 (8), 1480-1490.

70.Lijuan Ma,# Xiaoling Li,# Yi Wang, Wenjie Zheng and Tianfeng Chen*. Cu(II) inhibits hIAPP fibrillation and promotes hIAPP-induced beta cell apoptosis through induction of ROS-mediated mitochondrial dysfunction.Journal of Inorganic Biochemistry, 2014, 140, 143–152.

71.Xiaoling Li, Lijuan Ma, Wenjie Zheng, Tianfeng Chen*. Inhibition of islet amyloid polypeptide fibril formation by selenium-containing phycocyanin and prevention of beta cell apoptosis.Biomaterials, 2014, 35, 8596-8604.