杨亚慧

职称:博士 电话:
单位:化学与材料学院 邮箱:yyh@stu2017.jnu.edu.cn

研究方向:细胞通讯与药物设计

教育背景


09/2017–至今, 博士(再生医学),暨南大学

07/2016–06/2017, 研究助理,暨南大学化学系

09/2013–06/2016, 理学硕士(生物化学与分子生物学),暨南大学

09/2009-06/2013, 工学学士(生物工程),安阳工学院


发表论文


1.Yahui Yang; Qiang Xie *, ZhennanZhao, Lizhen He, Leung Chan, Yingxiang Liu, Yongle Chen, Mingjun Bai, Tao Pan, Yanni Qu, Long Ling, Tianfeng Chen *. Functionalized Selenium Nanosystem as Radiation Sensitizer of 125I Seeds for Precise Cancer Therapy. ACS Applied Materials & Interfaces, 2017, 9 (31), 25857–25869


2.Yahui Yang, Shulin Deng, Qinsong Zeng*, Weilie Hu, Tianfeng Chen*. Highly stable selenadiazole derivatives induce bladder cancer cell apoptosis and inhibit cell migration and invasion through activation of ROS-mediated signaling pathways. Dalton Transactions, 2016, 45(46), 18465-18475. (Inside front cover)


3. Xiaoyan Fu#, Yahui Yang#, Xiaoling Li, Haoqiang Lai, Yanyu Huang, Lizhen He, Wenjie Zheng, Tianfeng Chen *. RGD Peptide-conjugated Selenium Nanoparticles: Antiangiogenesis by Suppressing VEGF-VEGFR2-ERK/AKT Pathway. Nanomedicine: Nanotechnology, Biology, and Medicine, 2016, 12 (6), 1627–1639.


4. Yifan Wang, Wenying Li, Yahui Yang, Qinsong Zeng*, Ka-Hing Wong, Xiaoling Li*, Tianfeng Chen *. An integrin-targeting nanosystem as the carrier of selenadiazole derivative to induce ROS-mediated apoptosis in bladder cancer cells, from rational design to action mechanisms. J. Mater. Chem. B, 2015,3, 9374-9382.


5. Leung Chan, Lizhen He, Binwei Zhou, Shouhai Guan, Mingjun Bo, Yahui Yang, Ying Liu, Xiao Liu, Yanyang Zhang, Qiang Xie*, Tianfeng Chen*. Cancer-targeted Selenium Nanoparticles Sensitize Cancer Cells to Continuous γ Radiation to Achieve Synergetic Chemo-Radiotherapy, Chemistry-An Asian Journal, 2017, 12(23), 3053-3060.



专利发明


陈填烽,杨亚慧,曾钦松. 联苯并[1,2,5]硒二唑衍生物及其制备方法和应用(专利号:201610127128.3)


获奖情况


获得2018年学术创新成果奖;

获得2017年学术创新成果奖;

2016年傅家谟院士奖励基金三等奖

参加2016年第六届国际硒研讨会(The 6th International Selenium Conference)口头汇报,获“The Best Presenter ”称号;