1

Lizhen He, Qi Chen, Qichen Lu, Meijin Yang, Bin Xie, Tianfeng Chen*, Xun Wang*. Autophagy‐Inducing MoO3‐x Nanowires Boost Photothermal‐Triggered Cancer Immunotherapy. Angewandte Chemie. 2024, e202404822.

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Binhua Zou, Zushuang Xiong, Yanzi Yu, Sujiang Shi, Xiaoling Li*, Tianfeng Chen*. Rapid selenoprotein activation by selenium nanoparticles to suppresses osteoclastogenesis and pathological bone loss. Advanced Materials,2024,2401620.

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Rui Qiao#, Zhongwen Yuan#, Meijin Yang, Zhiying Tang, Lizhen He*, Tianfeng Chen*. Selenium-doped nanoheterojunctions for highly efficient cancer radiosensitization. Advanced Science, 2024, In press

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Haoqiang Lai, Ligeng Xu,* Chang Liu,   Sujiang Shi, Yalin Jiang, Yangyang Yu, Bo Deng, Tianfeng Chen*. Universal   selenium nanoadjuvant with immunopotentiating and redox-shaping activities   inducing high-quality immunity for SARS-CoV-2 vaccine. Signal Transduction   and Targeted Therapy, 2023, 8: 88.

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Wei Huang, Sujiang Shi, Haoran Lv, Zhenyu   Ju, Qinghua Liu*, Tianfeng Chen*. Tellurium-driven maple leaf-shaped   manganese nanotherapeutics reshape tumor microenvironment via chemical   transition in situ to achieve highly efficient radioimmunotherapy of triple   negative breast cancer, Bioactive Materials, 2023, in press.

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Leung Chan#, Yongkang Liu#, Muhe Chen#,   Yanhong Su, Junxian Guo, Liwen Zhu, Meixiao Zhan, Tianfeng Chen*, Ligong Lu*.   Cuproptosis-Driven Enhancement of Thermotherapy by Sequentially Response   Cu2-xSe via Copper Chemical Transition, Advanced Functional Materials,   2023, in press

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Fengzhi Zhao, Wei Huang, Lizhen He, Shiqing   Nie, Zhiting Sun, Tianfeng Chen*, Haiyan Yin*, Jianfu Zhao*. Reversing   lung cancer radioresistance by hyperpermeable tellurium nanotherapeutics via   remodeling tumor microenvironment, Nano Today, 2023, 50, 101819

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Chang Liu, Run Lin, Haoqiang Lai, Fen Pi,   Qian Xue, Tianfeng Chen*, Weiling He*. Thermosensitive selenium hydrogel   boosts antitumor immune response for hepatocellular carcinoma   chemoradiotherapy, Nano Today, 2023, 50, 101823.

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Zushuang Xiong^#, Hao Lin^#,   Hong Li, Binghua Zou, Bin Xie, Yanzi Yu, Lizhen He*, Tianfeng Chen*. Chiral   Selenium Nanotherapeutics Regulates Selenoproteins to Attenuate Glucocorticoid-induced   Osteoporosis, Advanced Functional Materials. 2023,  DOI:   10.1002/adfm.202212970

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Lizhen He, Jianfu Zhao, Hongjun Li, Bin   Xie, Ligeng Xu, Guanning Huang, Ting Liu, Zhen Gu*, Tianfeng Chen*, Metabolic   reprogramming of NK cells by black phosphorus quantum dots potentiates cancer   immunotherapy, Advanced Science, 2023, in press.

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Guanlin Li#, Sicheng Wu#, Wenzhe Chen#,   Xiaolu Duan, Xinyuan Sun, Shujue Li, Zanlin Mai, Wenzheng Wu, Guohua Zeng*,   Hongxing Liu*, Tianfeng Chen*. Designing intelligent nanomaterials to achieve   highly sensitive diagnoses and multimodality therapy of bladder cancer. Small   Methods, 2023, 2201313.

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Shuya Pan, Guanning Huang, Zhengwei Sun,   Xin Chen, Xinli Xiang, Wenxiao Jiang, Yanchao Xu, Tianfeng Chen*, Xueqiong   Zhu*. X-ray-responsive Zeolitic Imidazolate Framework-capped Nanotherapeutics   for Cervical Cancer-targeting Radiosensitization. Advanced Functional   Materials. 2023, in press

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Mingkai   Chen,^† Wenqiang Cao,^† Junping Wang,^† Fei   Cai, Liwen Zhu, Li Ma,* and Tianfeng Chen*. Selenium Atom-Polarization Effect   Determines TrxR-Specific Recognition of Metallodrugs. J Am Chem Soc, 2022,   144, 45, 20825–20833.

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Wenxiao   Jiang, Zhongyang Zhang, Miaomiao Ye, Shuya Pan, Guanning Huang, Tianfeng Chen^⁎,   Xueqiong Zhu^⁎, Morphology-directed radiosensitization of MoSe2   nanoplatforms for promoting cervical cancer radiotherapy, Nano Today,2022,   46, 101598.

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15         

Binhua Zou^#, Zushuang Xiong^#,   Lizhen He*, Tianfeng Chen*. Reversing Breast Cancer Bone Metastasis by Metal   Organic Framework-Capped Nanotherapeutics via Suppressing Osteoclastogenesis,   Biomaterials, 285,121549.

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16         

Zhenhuan Song, Ting Liu, Haoqiang Lai,   Xiaofeng Meng, Liu Yang, Jianyu Su*, and Tianfeng Chen*. A Universally   EDTA-Assisted Synthesis of Polytypic Bismuth Telluride Nanoplates with a   Size-Dependent Enhancement of Tumor Radiosensitivity and Metabolism In Vivo, ACS   Nano, 2022, 16, 3, 4379-4396

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Jiang Ouyang, Qingyue Bu, Na Tao, Mingkai   Chen, Haijun Liu, Jun Zhou, Jinggong Liu, Bo Deng, Na Kong, Xingcai Zhang*,   Tianfeng Chen*, Yihai Cao, Wei Tao*. A Facile and General Method for   Synthesis of Antibiotic-Free Protein-based Hydrogel: Wound Dressing for the   Eradication of Drug-Resistant Bacteria and Biofilms. Bioactive Materials,   2022, 18,446-458.

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Xiaosheng   Liang#, Ting Liu#, Linpeng Li#, Jieli Li, Shufang Li, Ke Zeng, Chao Song, Tianfeng   Chen*, and Yi Zou*, Translational selenium nanotherapeutics counter-acts   multiple risk factors to improve surgery-induced cognitive impairment. Chemical   Engineering Journal, 2022, 441, 135984. 

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Qi Chen#, Lizhen He#, Xiaoying Li, Ligeng   Xu* and Tianfeng Chen*. Ruthenium Complexes Boost NK Cell Immunotherapy via   Sensitizing Triple-negative Breast Cancer and Shaping Immuno-microenvironment,   Biomaterials, 2022, 281, 121371.

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20        

Guanning Huang†, Jiankun Zang†, Lizhen He†,   Huili Zhu†, Jiarun Huang, Zhongwen Yuan, Tianfeng Chen*, Anding Xu*, Bioactive   Nanoenzyme Reverses Oxidative Damage and Endoplasmic Reticulum Stress in   Neurons under Ischemic Stroke, ACS Nano, 2022, 16,   1, 431–452.

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Wei Huang, Lizhen He*, Zhongyang Zhang, Sujiang Shi, and Tianfeng Chen*.   Shape-Controllable Tellurium-Driven Heterostructures with Activated Robust   Immunomodulatory Potential for Highly Efficient Radiophotothermal Therapy of   Colon Cancer, ACS Nano, 2021, 15, 12, 20225–20241.

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Hui Yang#,   Chang Liu#, Yanjun Wu, Meng Yuan, Jiarun Huang, Yuhan Xia, Qinjie Ling, Peter   R. Hoffmann, Zhi Huang*, Tianfeng Chen*. Atherosclerotic   Plaque-targeted Nanotherapeutics Ameliorates Atherogenesis by Blocking   Macrophage-driven Inflammation, Nano Today,2022, 101351.

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Weiqiang Lin#, Hongxing Liu#, Lingwu Chen,   Junxing Chen, Dong Zhang, Qingqing Cheng, Fang Yang, Qinsong Zeng*, Tianfeng   Chen*. Pre-clinical MRI-guided intravesical instillation theranosis of   bladder cancer by tumor-selective oxygen nanogenerator, Nano Today,   2021, 38, 101124.

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Ting Liu, Xi Zhang, Lizhen He, Zehang   Zhang, Junmei Feng, Zhiming Lin*, Tianfeng Chen*. Specific Nanotherapeutics   for Highly Efficient Diagnosis and Treatment of Systemic Lupus Erythematosus,   Chemical Engineering Journal, 2022, 133095.

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Runcong Liu, Yongjun Peng, Ligong Lu,   Shaojun Peng*, Tianfeng Chen* and Meixiao Zhan*, Near-Infrared Light-Triggered   Nano-prodrug for Cancer Gas Therapy, Journal of Nanobiotechnology,   2021, 19:443. 

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Mingkai Chen, Xiaoting Huang, Huatian Shi, Jie   Lai, LiMa*, Tai-Chu Lau*, Tianfeng Chen*. Cr(V)–Cr(III) in-situ   transition promotes ROS generation to achieve efficient cancer therapy. Biomaterials,   2021, 276, 120991.

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27          

Lizhen He^#,   Guanning Huang^#, Hongxing Liu, Chengcheng Sang, Xinxin Liu, Tianfeng Chen*. Highly bioactive   zeolitic imidazolate framework-capped nanotherapeutics for efficient reversal   of reperfusion-induced injury in ischemic stroke.Science   Advances, 2020; 6: eaay9751.

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Wei Huang,   Lizhen He, Jiang Ouyang, Qi Chen, Chuang Liu, Wei Tao*, and Tianfeng Chen*.   Triangle-Shaped Tellurium Nanostars Potentiate Radiotherapy by Boosting   Checkpoint Blockade Immunotherapy. Matter, 2020, 3, 1725-1753.

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Zhongyang Zhang, Zhongmin Tang, Nika   Farokhzad, Tianfeng Chen,* and Wei Tao*. Sensitive, Rapid, Low-Cost,   and Multiplexed COVID-19 Monitoring by the Wireless Telemedicine Platform. Matter,   2020, 3, 1818–1831.

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Leung Chan#, Xiaodan Chen#, Pan Gao, Jun   Xie, Zhongyang Zhang, Jianfu Zhao, Tianfeng Chen*. Coordination-Driven   Enhancement of Radiosensitization by Black Phosphorus via Regulating Tumor   Metabolism. ACS Nano, 2021, 15, 2, 3047

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Jiang Ouyang, Ling Zhang, Leijiao Li,   Zhongmin Tang, Xiaoyuan Ji, Chan Feng, Na Tao, Na Kong, Tianfeng Chen*,   You-Nian Liu*, Wei Tao*. Cryogenic Exfoliation of 2D Stanene Nanosheets for   Cancer Theranostics. Nano-Micro Letters, 2021, 13:90.

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Ting Liu#, Ligeng Xu#, Lizhen He,   Jianfu Zhao, Zehang Zhang, Qi Chen, Tianfeng Chen*. Selenium   Nanoparticles Regulates Selenoprotein to Boost Cytokine-Induced Killer   Cells-Based Cancer Immunotherapy. Nano Today, 2020, 35, 100975.

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Zhuo Wang‡, Lizhen He‡, Bingqing Liu,Li-Peng Zhou, Li-Xuan Cai, Shao-Jun Hu, Xiao-Zhen Li, Zhikai Li,   Tianfeng Chen,* Xiaopeng Li,*Qing-Fu Sun*. Coordination-Assembled   Water-Soluble Anionic Lanthanide Organic Polyhedra for Luminescent Labeling   and Magnetic Resonance Imaging. J. Am. Chem. Soc., 2020, 142, 38,   16409–16419.

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Hao-Yan Yin, Jiu-Jiao Gao, Xuemin Chen, Bin   Ma, Zi-Shu Yang, Juan Tang, Bing-Wu Wang,    Tianfeng Chen*, Chu Wang*, Song Gao, Jun-Long Zhang*. A   Gallium(III) Complex that Engages Protein Disulfide Isomerase A3 (PDIA3) as   an Anticancer Target. Angew Chem Int Edit, 2020, 59, 20147-20153.

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Liu, Chang; Lai, Haoqiang; Chen,   Tianfeng*. Boosting Natural Killer Cell-Based Cancer Immunotherapy with   Selenocystine/Transforming Growth Factor-Beta Inhibitor-Encapsulated   Nanoemulsion. ACS Nano, 2020, 14, 9, 11067.

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Jing Wang, Yanzhou Chang, Hui Luo, Wenxiao   Jiang, Ligeng Xu, Tianfeng Chen*, Xueqiong Zhu*. Designing Immunogenic   Nanotherapeutics for Photothermal-Triggered Immunotherapy Involving Reprogramming   Immunosuppression and Activating Systemic Antitumor Responses. Biomaterials,   2020, 120153.

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Hongxing Liu†, Chaoming Mei†, Xuanru Deng,   Weiqiang Lin, Lizhen He, Tianfeng Chen*. Rapid visualizing and pathological   grading of bladder tumor tissues by simple nanodiagnostics, Biomaterials,   2021, 264, 120434.

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Zhennan   Zhao, Pan Gao, Li M* and Tianfeng   Chen*. A highly X-ray sensitive iridium prodrug for visualized tumor   radiochemotherapy. Chemical Science,   2020, 11, 3780 - 3789

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Lizhen He, Li-Xuan Cai, Meng-Hua Li,   Guang-Lu Zhang, Li-Peng Zhou, Tianfeng Chen*, Mei-Jin Lin* and Qing-Fu   Sun*. Designing a highly stable coordination-driven metallacycle for   imaging-guided photodynamic cancer theranostics, Chemical Science, 2020, 11, 7940-7949.

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JuanjuanLi, TianfengChen*.   Transition metal complexes as photosensitizers for integrated cancer   theranostic applications, Coordination Chemistry Reviews, 2020, 418,   213355.

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41 

Yuanyuan You, Zhennan Zhao, Lizhen He,   Zhibo Sun, Dong Zhang, Changzheng Shi, Qingqing Cheng, Yiyong Liu, Liangping   Luo, Tianfeng Chen*. Long-term   Oxygen Storage Nanosystem for Near-Infrared Light-Triggered Oxygen Supplies   to Antagonize Hypoxia-induced Therapeutic Resistance in Nasopharyngeal   Carcinoma. Advanced Functional Materials. 2020, 2002369.

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Yanyu   Huang^†, Yuanting Fu^†, Mengting Li, Dawei Jiang,   Christopher J. Kutyreff, Jonathan W. Engle, Xiaoli Lan, Weibo Cai*, Tianfeng Chen*. Chirality-driven   transportation and oxidation prevention by chiral selenium nanoparticles. Angew Chem Int Edit, 2020, 59, 4406-4414. Frontispiece

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Yanhong Duo^#, Yanyu Huang^#,   Weiyuan Liang^#, Riming Yuan, Yang Li, Tianfeng Chen*, Han   Zhang*. Ultraeffective Cancer Therapy with an Antimonene-Based X-Ray   Radiosensitizer. Advanced Functional Materials. 2019, 1906010.

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Hongxing Liu, Weiqiang Lin, Lizhen He*, Tianfeng   Chen*. Radiosensitive Core/Satellite Ternary Heteronanostructure for   Multimodal Imaging-Guided Synergistic Cancer Radiotherapy. Biomaterials,   2020, 119545.

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Chengli Dai †,   ZhengTang †, Xiaoling Li, Tianfeng Chen*.   High-pressure homogenization and tailoring of size-tunable Ganoderma   lucidum spore oil nanosystem for enhanced anticancer therapy. Chemical   Engineering Journal, 2021, 406, 127125

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Riming Yuan†, Yanyu   Huang†, Leung Chan, Dihao He, Tianfeng   Chen*. Engineering EHD1-Targeted Natural Borneol Nanoemulsion Potentiates   Therapeutic Efficacy of Gefitinib against Nonsmall Lung Cancer. ACS   Applied Materials & Interfaces, 2020, 12, 45714-45727

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Lanhai Lai, Zushuang Xiong, Li Ma*, Tianfeng   Chen*. Smart Microenvironment-Responsive Organocopper (II) Supramolecular   Polymers to Regulate the Stability and Anticancer Efficacy by Different   Substituents. ACS Applied Materials & Interfaces, 2020, 12,   40013-40020

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Yahui Yang, Yifan Wang, Ligeng Xu*, Tianfeng   Chen*. Dual-functional Se/Fe complex facilitates TRAIL treatment against   resistant tumor cells via modulating cellular endoplasmic reticulum stress. Chinese Chemical Letters, 2020, 31, 1801-1806

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Haoqiang Lai, Xiaobin Zhang, Zhenhuan Song,   Zhongwen Yuan, Lizhen He*, Tianfeng Chen*. Facile synthesis of   antioxidative nanotherapeutics using a microwave for efficient reversal of   cisplatin-induced nephrotoxicity. Chemical Engineering Journal, 2020, 391, 123563

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Yuanwei Liang, Delong Zeng, Yuanyuan You,   Bin Ma, Xiaoling Li, Tianfeng Chen*. Designing Dihydrofolate Reductase   Inhibitors as X-ray Radiosensitizers to Reverse Radioresistance of Cervical   Cancer. ACS Medicinal Chemistry Letters, 2020, 11, 1421-1428

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Liyuan Hou, Wei Huang, Jiaqi Cheng, Xuanru   Deng, Haoqiang Lai, Zhen Chen, Zepang Zhan, Pengju Feng, Yiqun Li, Fang   Yang*, Tianfeng Chen*. The investigation and bioorthogonal anticancer   activity enhancement of a triphenylphosphine-labile prodrug of   seleno-combretastatin-4. Chemical Communications, 2020, 56,   14495-14498

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Haoqiang Lai, Chang Liu, Liyuan Hou, Wenwei   Lin, Tianfeng Chen*, An Hong*. TRPM8-regulated calcium mobilization   plays a critical role in synergistic chemosensitization of Borneol on   Doxorubicin. Theranostics, 2020, 10, 10154

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Jinggong Liu, Yongjin Li, Song Chen,   Yongpeng Lin, Haoqiang Lai, Bolai Chen*, Tianfeng Chen*. Biomedical   Application of Reactive Oxygen Species–Responsive   Nanocarriers in Cancer, Inflammation, and Neurodegenerative Diseases. Frontiers   in Chemistry, 2020, 8, 838

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Fan Yang, Jiarun Huang, Hongxing Liu,   Weiqiang Lin, Xiaoling Li*, Xueqiong Zhu, Tianfeng Chen*.   Lentinan-functionalized selenium nanosystems with high permeability   infiltrate solid tumors by enhancing transcellular transport. Nanoscale,   2020, 12, 14494-14503

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Haoqiang Lai, Delong Zeng, Chang Liu, Qi   Zhang, and Tianfeng Chen*. Selenium-containing Ruthenium Complex   synergizes with Natural Killer Cells to Enhance Immunotherapy Against   Prostate Cancer via Activating TRAIL/FasL Signaling, Biomaterials,   2019,219, 119377

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Yi Hu#,   Ting Liu#, Jingxia Li#, Fengyi Mai, Jiawei Li, Yan Chen, Yanyun Jing, Xin   Dong, Li Lin, Junyi He, Yan Xu, Changliang Shan, Jianlei Hao, Zhinan Yin,   Tianfeng Chen*, Yangzhe Wu*. Selenium nanoparticles potentiate γδ T cell   anti-tumor cytotoxicity by upregulation of tubulin-a acetylation, Biomaterials,   2019, 119397.

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Lizhen He, Tianqi Nie, Xiaojun Xia, Ting   Liu, Yanyu Huang, Xiaojuan Wang, Tianfeng   Chen*. Designing Bioinspired 2D MoSe2 Nanosheet for Efficient   Photothermal-Triggered Cancer Immunotherapy with Reprogramming   Tumor-associated Macrophages.Advanced Functional   Materials. 2019, 1901240. (Back Cover)

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Chengli Dai, Lizhen He, Bin Ma, Tianfeng   Chen*. Facile Nanolization Strategy for Therapeutic Ganoderma Lucidum   Spore Oil to Achieve Enhanced Protection against Radiation-Induced Heart   Disease, Small, 2019, 1902642.

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Pengju Feng,* Guojian Ma, Xiaoguang Chen,   Xing Wu, Ling Lin, Peng Liu and Tianfeng   Chen* Electro-oxidative and Regioselective C-H Azolation of Phenol and   Aniline Derivatives, Angew Chem Int Edit, 2019,   58, 8400-8404.

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Chan, Leung ; Gao, Pan ; Zhou, Wenhua ;   Mei, Chaoming ; Huang, Yanyu; Yu, Xue-Feng*; Chu, Paul; Chen, Tianfeng*. Sequentially Triggered Delivery System of Black   Phosphorus Quantum Dots with Surface Charge Switching Ability for Precise   Tumor Radiosensitization. ACS Nano, 2018, 12,   12401–12415.

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Chaoming   Mei, Ni Wang, Xueqiong Zhu, Ka-Hing Wong, Tianfeng Chen*.   Photothermal-controlled Nanotubes with Surface Charge Flipping Ability for   Precise Synergistic Therapy of Triple-negative Breast Cancer. Advanced Functional Materials. 2018, 1805225.

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Lizhen He, Tianfeng Chen*, Yuanyuan   You, Hao Hu, Wenjie Zheng, Wai-Lun Kwong, Taotao Zou and Chi-Ming Che*. A Cancer-Targeted   Nanosystem for Delivery of Anti-Cancer Gold(III) Complexes: Enhanced   Selectivity and Apoptosis-Inducing Efficacy of Gold(III) Porphyrin. Angew Chem Int Edit, 2014, 53(46), 12532-12536.

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Wen Liu, Xiaoling Li, Yum-Shing Wong,   Wenjie Zheng*, Yibo Zhang, Wenqiang Cao, Chen Tianfeng*. Selenium   nanoparticles as a carrier of 5-Fluorouracil to achieve anticancer synergism.   ACS Nano, 2012, 6 (8), 6578–6591.

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