胡晓丽

职称:博士 电话:
单位:暨南大学化学系、温州医科大学妇产科系联合培养 邮箱:huxiaoli2016@126.com

研究方向:妇科肿瘤学

教育背景


2017/09-至今,温州医科大学,妇产科学,博士在读,导师:朱雪琼/陈填烽

2015/09-2017/06,温州医科大学,妇产科学,硕士,导师:朱雪琼

2011/07-2015/07,温州市人民医院,妇产科,住院医师

2006/09-2011/06,温州医学院,妇产科专业,学士


科研项目


  1. 浙江省医药卫生科技计划项目,2017KY485,PRDX1对宫颈癌化疗药物敏感性的影响及其相关机制的研究,2017/01-2018/12,配套3万,在研,主持;


  1. 温州市科技局医疗卫生科技项目,Y20160339,Peroxiredoxins对宫颈鳞癌生物学行为影响的研究,2017/01-2018/12,自筹,在研,主持;


  2. 国家自然科学基金面上项目,81671809,构建基于TRAIL-exosome的siRNA和Cisplatin共载纳米系统及治疗耐药宫颈癌的研究,2017/01-2019/12,配套58万,在研,参加;


  1. 国家自然科学基金青年科学基金项目,81602305,宫颈癌中TGF-β1诱导肿瘤干细胞介导顺铂耐药的分子机制研究,2018/01-2020/12,配套17万,在研,参加;


  2. 国家自然科学基金青年科学基金项目,81701828,构建基于间充质干细胞-外泌体杂交膜包覆的siRNA纳米系统及其在卵巢癌治疗中的应用,2018/01-2020/12,配套20万,在研,参加。


发表论文


    1. Zhou Q#, Hu X#, Zhou J, Zhao M, Zhu X, Zhu X*. Human papillomavirus DNA in surgical smoke during cervical loop electrosurgical excision procedures and its impact on the surgeon. Cancer Manag Res. 2019;11:3643-3654.


    2. Hu X, Liu H, Ye M, Zhu X*. Prognostic value of microvessel density in cervical cancer. Cancer Cell Int. 2018;18:152.


    3. Hu X, Li S, Zhou L, Zhao M, Zhu X*. Effect of vitamin E supplementation on uterine cervical neoplasm: A meta-analysis of case-control studies. PLoS One. 2017;12(8):e0183395.

    4. Lu e#, Hu X#, Zhu X*.Effect of peroxiredoxin 1 expression on the biological behavior of cervical cancer cells and the underlying mechanisms. Journal of cancer. 2019.

    .

  1. 胡晓丽,盛波,朱雪琼.选择性孕酮受体调节剂在子宫肌瘤治疗中的应用研究发展.浙江医学.40(24):2714-2718.

  2. 胡晓丽,朱雪琼. Hedgehog信号通路在妇科恶性肿瘤中的研究. 医学研究杂志. 2016;45(10):19-23.


    非第一作者论文:

(1)Liu Y, Song Y, Hu X, Yan L, Zhu X. Awareness of surgical smoke hazards and enhancement of surgical smoke prevention among the gynecologists. J Cancer. 2019;10(12):2788-2799.


(2)Liu Y, Song Y, Ye M, Hu X, Wang ZP, Zhu X. The emerging role of WISP proteins in tumorigenesis and cancer therapy. J Transl Med. 2019;17(1):28.


(3)Chetry M, Thapa S, Hu X, Song Y, Zhang J, Zhu H, Zhu X. The Role of Galectins in Tumor Progression, Treatment and Prognosis of Gynecological Cancers. J Cancer. 2018;9(24):4742-4755.

(4)Zhou L, Xu X, Liu H, Hu X, Zhang W, Ye M, Zhu X. Prognosis Analysis of Histone Deacetylases mRNA Expression in Ovarian Cancer Patients. J Cancer. 2018;9(23):4547-4555.


(5)Zhao C, Lu E, Hu X, Cheng H, Zhang JA, Zhu X. S100A9 regulates cisplatin chemosensitivity of squamous cervical cancer cells and related mechanism. Cancer Manag Res. 2018;10:3753-3764.


(6)Li S, Hu X, Ye M, Zhu X. The prognostic values of the peroxiredoxins family in ovarian cancer. Biosci Rep. 2018;38(5). pii: BSR20180667.


(7)Chetry M, Li S, Liu H, Hu X, Zhu X. Prognostic values of aquaporins mRNA expression in human ovarian cancer. Biosci Rep2.535. 2018 Apr 27;38(2). pii: BSR20180108.

(8)Shen Q, Hu X, Zhou L, Zou S, Sun LZ, Zhu X. Overexpressionof the 14-3-3γ protein in uterine leiomyoma cells results in growth retardation and increased apoptosis. Cell Signal. 2018;45:43-53.


(9)Zhang W, Zhang Y, Hu X, Cheng H, Hua Y, Zhu X*. Danshen extract regulates the expression of aquaporin 3 in human amniotic epithelial cells. Front Biosci (Landmark Ed). 22, 1138-1147.


(10)Zhu H, Luo H, Zhu X, Hu X, Zheng L, Zhu X*. Pyruvate kinase M2 (PKM2) expression correlates with prognosis in solid cancers: a meta-analysis. Oncotarget. 2017;8: 1628-1640.


(11)Shen Q, Ye W, Hu X, Zhao C, Zhou L, Zhu X*. The Effects of Guizhi Fuling Capsule Drug Serum on Uterine Leiomyoma Cells and Its Mechanism. Evid Based Complement Alternat Med. 2016;2016:2393640.


(12)Zhu H, Zhu X, Zheng L, Hu X, Sun L, Zhu X*. The role of the androgen receptor in ovarian cancer carcinogenesis and its clinical implications. Oncotarget. 2016 Oct 11. doi: 10.18632/oncotarget.12561. 


(13)Hua Y, Zhang W, Hu X, Yang A, Zhu X*. The use of misoprostol for cervical priming prior to hysteroscopy: a systematic review and analysis. Drug Des Devel Ther. 2016 Sep 6;10:2789-2801.


(14)Jiang W, Shen Z, Luo H, Hu X, Zhu X*. Comparison of polyvinyl alcohol and tris-acryl gelatin microsphere materials in embolization for symptomatic leiomyomas: a systematic review. Minim Invasive Ther Allied Technol. 2016,19:1-12.


(15)Zhu H, Luo H, Zhang W, Shen Z, Hu X, Zhu X. Molecular mechanisms of cisplatin resistance in cervical cancer. Drug Des Devel Ther. 2016;10:1885-95.


(16)Zhang W, Shen Z, Luo H, Hu X, Zheng L, Zhu X*. The benefits and side effects of bevacizumab for the treatment of recurrent ovarian cancer. Curr Drug Targets. 2016.


(17)Zhu H, Luo H, Shen Z, Hu X, Sun L, Zhu X*. Transforming growth factor-β1 in carcinogenesis, progression, and therapy in cervical cancer. Tumour Biol. 2016,37(6):7075-83.


(18)Hua Y, Zhang W, Hu X, Yang A, Zhu X*. The use of misoprostol for cervical priming prior to hysteroscopy: systematic review and analysis.Drug Des Devel Ther. 2016,10:2789-2801.


获奖情况


12018年,浙江省医学会妇科肿瘤学分会妇科肿瘤论文比赛二等奖

22016年、2017年,温州医科大学学业奖学金一等奖

32017年,温州医科大学叶碧绿奖学金